Roxicef S125/Roxicef S250: Cefuroxime should not be given to patients who are hypersensitive to it or to other cephalosporins. About 10% of penicillin-sensitive patients may also be allergic to cephalosporins although the true incidence is uncertain; great care should be taken if cefuroxime is to be given to such patients. Care is also necessary in patients with a history of allergy.
Roxicef: Penicillin-sensitive patients, gastrointestinal disease especially colitis. Monitor kidney function. Prolonged treatment. Pregnancy and lactation. Children below 3 months.